Document Detail

Cerebral embolism following thrombolytic therapy for acute myocardial infarction: the second reported case.
MedLine Citation:
PMID:  20532455     Owner:  NLM     Status:  MEDLINE    
ST-elevation myocardial infarction (STEMI), caused by acute occlusion of the infarct-related coronary artery, is an emergency condition. The primary therapy is restoration of full antegrade flow by either percutaneus coronary intervention (PCI) or thrombolytic therapy (TT). Although primary PCI is superior to TT in patients with STEMI, there are many limitations in clinical practice. TT decreases mortality in STEMI patients, but as experience with thrombolytic agents grows, the potential risks of serious side effects become more apparent. The major complications are bleeding, hypotension and skin rash. We report on a case of cerebrovascular accident (CVA) caused by cerebral emboli following TT. We concluded that the fact that the patient was in arterial fibrillation (AF) was a major contributing factor to her CVA. This is an extremely rare condition, and our case appears to be the second one reported on in the literature.
M Bostan; A Kanat; M Sen; H Kazdal; H Bostan
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cardiovascular journal of Africa     Volume:  21     ISSN:  1995-1892     ISO Abbreviation:  Cardiovasc J Afr     Publication Date:    2010 May-Jun
Date Detail:
Created Date:  2010-06-09     Completed Date:  2010-09-28     Revised Date:  2010-12-06    
Medline Journal Info:
Nlm Unique ID:  101313864     Medline TA:  Cardiovasc J Afr     Country:  South Africa    
Other Details:
Languages:  eng     Pagination:  155-7     Citation Subset:  IM    
Department of Cardiology, Rize University Medical School, Rize, Turkey.
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MeSH Terms
Aged, 80 and over
Atrial Fibrillation / complications,  diagnosis
Fibrinolytic Agents / adverse effects*
Intracranial Embolism / etiology*,  radiography
Myocardial Infarction / complications,  drug therapy*
Stroke / etiology*,  radiography
Thrombolytic Therapy / adverse effects*
Tomography, X-Ray Computed
Reg. No./Substance:
0/Fibrinolytic Agents
Comment In:
Cardiovasc J Afr. 2010 Sep-Oct;21(5):262   [PMID:  20972513 ]

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