Document Detail


Cerebral border zones between distal end branches of intracranial arteries: MR imaging.
MedLine Citation:
PMID:  18055872     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study had institutional review board approval; informed consent was obtained from all participants. The study purpose was to prospectively determine whether a longer arterial transit time (ATT), from the proximal vasculature in the neck toward the distal end branches of the intracranial arteries, can be utilized to identify cerebral border zone regions. A magnetic resonance (MR) imaging method based on noninvasive arterial spin-labeling (ASL) perfusion MR imaging with image acquisition at a series of increasing delay times was used to quantify regional ATTs. Fifteen healthy volunteers (age range, 22-34 years; nine men, six women) were included. ASL perfusion MR imaging demonstrated an increase in ATT in the cerebral border zone regions, extending from the frontal and occipital horns of the lateral ventricle to the frontal and parietooccipital cortices, relative to ATT in non-border zone regions. Cerebral blood flow and arterial blood volume in these anterior and posterior border zone regions were significantly lower (P < .001) than in non-border zone regions.
Authors:
Jeroen Hendrikse; Esben Thade Petersen; Peter Jan van Laar; Xavier Golay
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-11-30
Journal Detail:
Title:  Radiology     Volume:  246     ISSN:  1527-1315     ISO Abbreviation:  Radiology     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-01-31     Completed Date:  2008-02-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  572-80     Citation Subset:  AIM; IM    
Copyright Information:
(c) RSNA, 2007.
Affiliation:
Department of Radiology, University Medical Center Utrecht, Hp E 01.132, PO Box 85500, 3508 GA Utrecht, the Netherlands. j.hendrikse@umcutrecht.nl
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MeSH Terms
Descriptor/Qualifier:
Adult
Algorithms
Artificial Intelligence
Cerebral Arteries / anatomy & histology*
Cerebral Cortex / blood supply*
Female
Humans
Image Enhancement / methods*
Image Interpretation, Computer-Assisted / methods*
Imaging, Three-Dimensional / methods*
Magnetic Resonance Imaging / methods*
Male
Pattern Recognition, Automated / methods*
Reproducibility of Results
Sensitivity and Specificity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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