Document Detail


Cerebral blood flow and neuropsychological functioning in elderly vascular disease patients.
MedLine Citation:
PMID:  22149630     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
This study was designed to determine the relationships between positron emission tomography (PET)-based quantitative measures of cerebral blood flow and cerebrovascular reserve and neuropsychological functioning in elderly individuals with atherosclerotic vascular disease. It was hypothesized that cerebrovascular function would be significantly associated with neuropsychological functioning. Results showed that both baseline global cerebral blood flow and cerebrovascular reserve were significantly associated with global neuropsychological functioning, when controlling for age and sex. Cerebrovascular reserve was additionally associated with performance on measures of memory and attention. Additional research is needed to determine whether measures of cerebral blood flow can be used to predict cognitive decline.
Authors:
David J Moser; Laura L Boles Ponto; Ivy N Miller; Susan K Schultz; Yusuf Menda; Stephan Arndt; Peggy C Nopoulos
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-13
Journal Detail:
Title:  Journal of clinical and experimental neuropsychology     Volume:  -     ISSN:  1744-411X     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8502170     Medline TA:  J Clin Exp Neuropsychol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
a Department of Psychiatry , University of Iowa Carver College of Medicine , Iowa City , IA , USA.
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