Document Detail

Cerebral blood flow: measurement with xenon-enhanced dynamic helical CT.
MedLine Citation:
PMID:  7892495     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To improve CT number reproducibility in helical CT, a newly developed controlled-orbit helical scan mechanism was applied. The authors developed a method for volumetric measurement of cerebral blood flow (CBF) with dynamic helical computed tomography (CT) after inhalation of xenon gas. MATERIALS AND METHODS: In three subjects (two healthy men aged 22 and 38 years and a 7-year-old girl with moyamoya disease), six helical scans were obtained during 6-minute xenon inhalation, and CT scans with 41 sections in 2-mm increments were reconstructed from each scan. Conventional CBF calculation was then applied to the CT images. RESULTS: CBF maps of 40 sections for each subject of sufficient diagnostic quality were obtained with a 39-cGy radiation dose. The spatial resolution was 2.5 line pairs per centimeter. CONCLUSION: This volumetric CBF mapping method is applicable in clinical practice because of the short examination time and acceptable radiation dose.
K Nambu; R Suzuki; K Hirakawa
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Radiology     Volume:  195     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1995 Apr 
Date Detail:
Created Date:  1995-04-14     Completed Date:  1995-04-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  53-7     Citation Subset:  AIM; IM    
Medical Systems Engineering Department II, Toshiba Corporation, Tochigi, Japan.
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MeSH Terms
Cerebrovascular Circulation / physiology*
Image Processing, Computer-Assisted*
Models, Structural
Moyamoya Disease / radiography
Radiation Dosage
Time Factors
Tomography, X-Ray Computed / methods*
Xenon / diagnostic use*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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