| Cerebral blood flow index image as a simple indicator for the fate of acute ischemic lesion. | |
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MedLine Citation:
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PMID: 14753444 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND PURPOSE: To evaluate the feasibility of utilizing cerebral blood flow (CBF) index images, we attempted to investigate 1) whether CBF index images can reveal the resulting infracted area, 2) whether the CBF index can correlate other modality (SPECT). METHODS: DWI and DPI were obtained in 17 patients within 12 hours of stroke onset and follow up MRI. On three DPI delivered images, namely relative regional cerebral blood volume (rrCBV), uncorrected mean transit time (MTTu) and CBF index images, correlations between initial lesion volume of and follow up infarction volume of three images and rCBF images delivered with singular value decomposition (SVD) methods were assessed. Then 99mTc-ECD SPECT was taken immediately after MRI to correlate to MRI data. RESULTS: Among the three images, lesion volume of CBF index images against follow up infarct volume had the highest correlation (r = 0.995) to a linear fit and the slope was closest to 1.0 (0.91) and had identical accuracy to the regression coefficient of rCBF images. CBF index well correlated to SPECT delivered CBF. CONCLUSION: CBF index images can accurately predict final infarct volume. Evaluating CBF index images together with DWI can guide the initial assessment in the acute stage of cerebral ischemia. |
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Authors:
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H Igarashi; M Hamamoto; H Yamaguchi; S Ookubo; J Nagashima; H Nagayama; S Amemiya; K Arii; M Sakamaki; Y Katayama |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta neurochirurgica. Supplement Volume: 86 ISSN: 0065-1419 ISO Abbreviation: Acta Neurochir. Suppl. Publication Date: 2003 |
Date Detail:
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Created Date: 2004-02-02 Completed Date: 2004-03-09 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 100962752 Medline TA: Acta Neurochir Suppl Country: Austria |
Other Details:
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Languages: eng Pagination: 241-6 Citation Subset: IM |
Affiliation:
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The Second Internal Medicine, Nippon Medical School, Tokyo, Japan. higara@nms.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Brain / pathology, radionuclide imaging Brain Ischemia / physiopathology* Cerebral Infarction / diagnosis Cerebrovascular Circulation* Diffusion Magnetic Resonance Imaging Echo-Planar Imaging Humans Magnetic Resonance Angiography Prognosis Radiopharmaceuticals / diagnostic use Technetium Tc 99m Exametazime / diagnostic use Tomography, Emission-Computed, Single-Photon |
| Chemical | |
Reg. No./Substance:
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0/Radiopharmaceuticals; 100504-35-6/Technetium Tc 99m Exametazime |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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