Document Detail


Cerebral blood flow in Sneddon syndrome.
MedLine Citation:
PMID:  8113897     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sneddon syndrome is defined as a clinical entity consisting of livedo racemosa generalisata (LRG) and cerebrovascular lesions, which often lead to physical and mental handicaps. Four patients with LRG and the suspected diagnosis of Sneddon syndrome had HMPAO-SPECT studies. The patients underwent CT and/or MR brain imaging and three patients had Duplex sonography of the cerebral arteries (TCD). Brain SPECT was abnormal in all patients, whereas CT/MRI revealed a cerebral lesion in only one patient and all TCD studies were normal. HMPAO-SPECT is valuable in detecting disturbed regional cerebral blood flow before irreversible ischemic insults occur, thus allowing the diagnosis of Sneddon syndrome at an early stage.
Authors:
C Menzel; U Reinhold; F Grünwald; A von Smekal; M Uerlich; O Rieker; A L Hotze; H J Biersack
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of nuclear medicine : official publication, Society of Nuclear Medicine     Volume:  35     ISSN:  0161-5505     ISO Abbreviation:  J. Nucl. Med.     Publication Date:  1994 Mar 
Date Detail:
Created Date:  1994-03-31     Completed Date:  1994-03-31     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0217410     Medline TA:  J Nucl Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  461-4     Citation Subset:  IM    
Affiliation:
Department of Nuclear Medicine, University of Bonn, Germany.
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MeSH Terms
Descriptor/Qualifier:
Adult
Brain / pathology,  radionuclide imaging*
Cerebrovascular Circulation / physiology*
Cerebrovascular Disorders / diagnosis,  physiopathology,  radionuclide imaging*
Diagnostic Imaging
Female
Humans
Organotechnetium Compounds / diagnostic use*
Oximes / diagnostic use*
Skin Diseases, Vascular / diagnosis,  physiopathology,  radionuclide imaging*
Syndrome
Technetium Tc 99m Exametazime
Tomography, Emission-Computed, Single-Photon
Chemical
Reg. No./Substance:
0/Organotechnetium Compounds; 0/Oximes; 100504-35-6/Technetium Tc 99m Exametazime

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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