| Cerebral beta-endorphin levels in a woman with Prader-Labhart-Willi syndrome. | |
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MedLine Citation:
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PMID: 2530599 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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By means of a specific two-site immunoradiometric assay, we explored the beta-endorphin levels in various brain regions of a patient affected by Prader-Labhart-Willi Syndrome. The rank of the beta-endorphin levels of five cerebral zones (hypothalamus, substantia grisea centralis, pons dorsalis, medulla oblongata dorsalis medialis, thalamus medialis) of the patient was homologous to that of subjects without the syndrome, except for the medulla oblongata dorsalis medialis. In patient with the Prader-Labhart-Willi Syndrome this region had a higher ranking level than in subjects without it. However, a functional meaning cannot be attributed to such difference because the patient of this study did not exhibit neurological disturbances relating to elevated beta-endorphin levels in the medullary region investigated. |
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Authors:
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A Pasi; P Mehraein; C Gramsch; A Jehle; J Briner; M Häni; P Külling; R Hauri; F S Messiha |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Physiology & behavior Volume: 46 ISSN: 0031-9384 ISO Abbreviation: Physiol. Behav. Publication Date: 1989 Jul |
Date Detail:
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Created Date: 1989-12-21 Completed Date: 1989-12-21 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0151504 Medline TA: Physiol Behav Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 17-8 Citation Subset: IM |
Affiliation:
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Institute of Forensic Medicine, University of Zurich, Switzerland. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Brain / pathology* Brain Mapping Death, Sudden / pathology* Female Humans Immunoradiometric Assay Prader-Willi Syndrome / pathology* beta-Endorphin / metabolism* |
| Chemical | |
Reg. No./Substance:
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60617-12-1/beta-Endorphin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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