Document Detail

Cerebral atrophy and vigilance performance in patients with anorexia nervosa and bulimia nervosa.
MedLine Citation:
PMID:  2630934     Owner:  NLM     Status:  MEDLINE    
The relationship between ventricular size, as a measure of brain atrophy, and performance on a vigilance task was investigated in 39 patients with anorexia or bulimia nervosa during the acute stage of their illness. Compared to normal controls, the patients performed significantly more poorly in the cognitive task. Half of the patients displayed enlarged ventricles. However, the patients with ventricular dilatation did not perform worse in the cognitive test than patients with normally sized ventricles. Other clinical characteristics, such as symptom severity or duration of illness, were also not correlated with ventricular size. These results support the interpretation that cerebral atrophy per se does not have severe consequences on the neuropsychological or psychopathological status in eating disorder patients.
R G Laessle; J C Krieg; M M Fichter; K M Pirke
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neuropsychobiology     Volume:  21     ISSN:  0302-282X     ISO Abbreviation:  Neuropsychobiology     Publication Date:  1989  
Date Detail:
Created Date:  1990-05-07     Completed Date:  1990-05-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7512895     Medline TA:  Neuropsychobiology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  187-91     Citation Subset:  IM    
Max-Planck-Institute for Psychiatry, Munich, FRG.
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MeSH Terms
Anorexia Nervosa / physiopathology,  psychology*
Attention / physiology*
Brain / pathology*
Bulimia / physiopathology,  psychology*
Cerebral Ventricles / pathology
Delirium, Dementia, Amnestic, Cognitive Disorders / physiopathology,  psychology*
Neuropsychological Tests
Psychomotor Performance / physiology
Tomography, X-Ray Computed

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