| Cerebral amyloid angiopathy related inflammation: three case reports and a review. | |
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MedLine Citation:
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PMID: 20935328 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cerebral amyloid angiopathy related inflammation (CAA-I), previously described under various names, is a treatable encephalopathy usually occurring in older adults. Here, three patients are described with histopathologically confirmed CAA-I, and summarised data from the published literature are presented. CAA-I has a characteristic combination of clinical and radiological features. Definite diagnosis requires brain and leptomeningeal biopsy. A favourable response to immunosuppressive therapy is common and treatment without brain biopsy may be considered in selected patients. Diagnostic criteria for CAA-I are proposed. |
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Authors:
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Kong Khi Chung; Neil E Anderson; David Hutchinson; Beth Synek; P Alan Barber |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-10-09 |
Journal Detail:
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Title: Journal of neurology, neurosurgery, and psychiatry Volume: 82 ISSN: 1468-330X ISO Abbreviation: J. Neurol. Neurosurg. Psychiatr. Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2010-12-14 Completed Date: 2011-01-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2985191R Medline TA: J Neurol Neurosurg Psychiatry Country: England |
Other Details:
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Languages: eng Pagination: 20-6 Citation Subset: IM |
Affiliation:
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Department of Neurology, Auckland Hospital, Auckland, New Zealand. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Alzheimer Disease / pathology Anti-Inflammatory Agents / therapeutic use Blood Vessels / pathology Brain / pathology Cerebral Amyloid Angiopathy / drug therapy, pathology* Cerebral Cortex / pathology Cyclophosphamide / therapeutic use Dexamethasone / therapeutic use Fatal Outcome Female Headache / etiology Humans Immunosuppressive Agents / therapeutic use Inflammation / pathology* Magnetic Resonance Imaging Male Methylprednisolone / therapeutic use Middle Aged Paresis / etiology Prognosis Seizures / etiology Tomography, X-Ray Computed |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents; 0/Immunosuppressive Agents; 50-02-2/Dexamethasone; 50-18-0/Cyclophosphamide; 83-43-2/Methylprednisolone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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