Document Detail

Cerebral alveolar echinococcosis. A case report with MRI and review of the literature.
MedLine Citation:
PMID:  17641579     Owner:  NLM     Status:  MEDLINE    
Alveolar echinococcosis is an important zoonotic infection caused by the larval stage of the Echinococcus multilocularis. It is endemic to North America, Central Europa, Russia, China and Turkey. The liver and the lung are the organs most commonly involved. Cerebral alveolar echinococcosis is rare accounting for only 1% of cases. We present a 55-year-old patient with a right frontal mass. T2-weighted MRI series revealed a grape like multilobular, heterogeneous mass with low density. A diagnosis of glial tumor was made. The mass was totally removed. The histopathological examination showed a diffuse growth composed of compartments that are filled with a gelatinous matrix and many brood capsules and protoscolices filled with necrotic tissue. Histopathological findings were consistent with the diagnosis of alveolar echinococcosis. No postoperative complications were observed. There were no lesions in the liver and lungs. The patient was started on albendazole (ABZ) at a daily dosage of 800 mg for 3 months. The patient has remained free of any mass lesion for 5 years. Hypointense grape-like mass with calcification and surrounding white matter edema in T2-weighted MRI should suggest cerebral alveolar echinococcosis. Radical surgery and an adjuvant therapy with ABZ provides useful prolongation of life.
N Isik; G Silav; A Cerçi; P Karabagli; I Elmaci; M Kalelioglu
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of neurosurgical sciences     Volume:  51     ISSN:  0390-5616     ISO Abbreviation:  J Neurosurg Sci     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-07-20     Completed Date:  2008-01-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0432557     Medline TA:  J Neurosurg Sci     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  145-51; discussion 151     Citation Subset:  IM    
Department of Neurosurgery, SB. Goztepe Education and Research Hospital, Goztepe, Istanbul, Turkey.
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MeSH Terms
Albendazole / administration & dosage
Antiprotozoal Agents / administration & dosage
Brain Diseases / parasitology*,  surgery
Echinococcosis / drug therapy,  pathology*,  surgery
Echinococcus multilocularis*
Magnetic Resonance Imaging*
Middle Aged
Reg. No./Substance:
0/Antiprotozoal Agents; 54965-21-8/Albendazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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