Document Detail

Cerebral abscess caused by Cladosporium bantianum. Case report.
MedLine Citation:
PMID:  7043379     Owner:  NLM     Status:  MEDLINE    
A case is presented of a cerebral abscess in a 59-yr-old woman caused by the dematiaceous fungus Cladosporium bantianum (Sacc.) Borelli (= Cladosporium trichoides Emmons). The morphological and physiological properties of the isolate and its pathogenicity for experimental animals were investigated and compared with some other Cladosporium species. The neurotropism exhibited by C. bantianum in human infections was found also in the test animals. Despite surgical excision and therapy with the antifungal drugs amphotericin B and flucytosine, the case had a fatal outcome, the patient dying from a pulmonary embolism 6 mth after the onset of symptoms. The clinical entity of central nervous system infections by dematiaceous fungi is discussed in relation to the present case.
E Wilson
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pathology     Volume:  14     ISSN:  0031-3025     ISO Abbreviation:  Pathology     Publication Date:  1982 Jan 
Date Detail:
Created Date:  1982-07-08     Completed Date:  1982-07-08     Revised Date:  2006-10-31    
Medline Journal Info:
Nlm Unique ID:  0175411     Medline TA:  Pathology     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  91-6     Citation Subset:  IM    
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MeSH Terms
Amphotericin B / therapeutic use
Brain Abscess / drug therapy,  microbiology*,  surgery
Cladosporium / isolation & purification*
Flucytosine / therapeutic use
Hydrocephalus / complications
Microbiological Techniques
Middle Aged
Mitosporic Fungi / isolation & purification*
Mycoses / complications,  drug therapy*
Pulmonary Embolism / complications
Reg. No./Substance:
1397-89-3/Amphotericin B; 2022-85-7/Flucytosine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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