Document Detail

Cerebral microembolism during coronary angiography: a randomized comparison between femoral and radial arterial access.
MedLine Citation:
PMID:  21393589     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND PURPOSE: Microemboli observed during coronary angiography can cause silent ischemic cerebral lesions. The aim of this study was to investigate if the number of particulate cerebral microemboli during coronary angiography is influenced by access site used.
METHODS: Fifty-one patients with stable angina pectoris referred for coronary angiography were randomized to right radial or right femoral arterial access. The number of particulate microemboli passing the middle cerebral arteries was continuously registered with transcranial Doppler.
RESULTS: The median (minimum-maximum range) numbers of particulate emboli were significantly higher with radial 10 (1-120) than with femoral 6 (1-19) access. More particulate microemboli passed the right middle cerebral artery with the radial access.
CONCLUSIONS: This study indicates that the radial access used for coronary angiography generates more particulate cerebral microemboli than the femoral access and thus may influence the occurrence of silent cerebral injuries.
Juliane Jurga; Jesper Nyman; Per Tornvall; Maria Nastase Mannila; Peter Svenarud; Jan van der Linden; Nondita Sarkar
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2011-03-10
Journal Detail:
Title:  Stroke; a journal of cerebral circulation     Volume:  42     ISSN:  1524-4628     ISO Abbreviation:  Stroke     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-04-26     Completed Date:  2011-06-30     Revised Date:  2011-09-09    
Medline Journal Info:
Nlm Unique ID:  0235266     Medline TA:  Stroke     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1475-7     Citation Subset:  IM    
Cardiology Unit, Department of Medicine, Karolinska University Hospital, Solna, N3:05, SE 171 76 Stockholm, Sweden.
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MeSH Terms
Angina Pectoris / radiography
Coronary Angiography / adverse effects*
Femoral Artery*
Intracranial Embolism / epidemiology*
Middle Aged
Radial Artery*
Retrospective Studies
Risk Factors
Comment In:
Stroke. 2011 Aug;42(8):e418; author reply e419   [PMID:  21737810 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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