Document Detail


Cerebral Microbleeds in Patients with Moyamoya-like Vessels Secondary to Atherosclerosis.
MedLine Citation:
PMID:  22246484     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Objective Hemorrhagic risk is unknown in patients with moyamoya-like vessels associated with atherosclerotic intracranial cerebral artery occlusion. This study was undertaken to investigate the association between moyamoya-like vessels and cerebral microbleeds (CMBs) in patients with atherosclerotic steno-occlusive disease. Methods The study population comprised 34 patients with steno-occlusive lesions in the intracranial cerebral artery caused by atherosclerosis. We evaluated the presence of moyamoya-like vessels at the base of the brain by cerebral angiography, and the presence of CMBs by T2*-weighted MRI. Patients were divided into 2 groups: those with and those without moyamoya-like vessels; clinical histories and the incidence of CMBs were compared between the groups. Results Sixteen patients had moyamoya-like vessels. Twelve of 16 patients with moyamoya-like vessels had a history of ischemic stroke or transient ischemic attack, whereas only 1 patient had a history of symptomatic cerebral hemorrhage. The incidence of CMBs did not differ between the 2 groups (31% vs. 28%, p=0.82). The location of CMBs varied and was not associated with the site of moyamoya-like vessels. Conclusion CMBs were not associated with moyamoya-like vessels in patients with atherosclerotic cerebral artery occlusion. These patients may not have a high risk of cerebral hemorrhage.
Authors:
Makiko Tanaka; Manabu Sakaguchi; Kaori Miwa; Kazuo Kitagawa
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Publication Detail:
Type:  Journal Article     Date:  2012-01-15
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  51     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2012  
Date Detail:
Created Date:  2012-01-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  167-72     Citation Subset:  IM    
Affiliation:
Department of Neurology, Osaka University Graduate School of Medicine, Japan.
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