Document Detail


Cerebellar liponeurocytoma (lipomatous medulloblastoma).
MedLine Citation:
PMID:  12717299     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Liponeurocytoma (lipomatous medulloblastoma) is an uncommon clinicopathologic entity. We report a case of cerebellar liponeurocytoma in an adult and attempt to better characterize this uncommon lesion. A 43-year-old woman presented with symptoms and signs of increased intracranial pressure and cerebellar dysfunction. CT and MRI showed a heterogeneous well-circumscribed mass in the left cerebellar hemisphere with hydrocephalus. Complete surgical excision of the tumor was accomplished through a suboccipital craniotomy. Pathological examination with immunohistochemical study revealed a medulloblastoma with neuronal, astrocytic and lipomatous differentiation. Postoperative radiation therapy was given. After surgery, the patient was followed up for a 16 month-period; symptoms improved dramatically and no evidence of tumor recurrence was found. Careful analysis of the histopathological and immunohistochemical studies correctly identifies liponeurocytoma (lipomatous medulloblastoma). To our knowledge, only 16 cases have been reported. Although this lesion appears to have a better prognosis than the conventional form of adult medulloblastoma, complete surgical removal with postoperative radiation therapy is recommended.
Authors:
A Akhaddar; I Zrara; M Gazzaz; B El Moustarchid; S Benomar; M Boucetta
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of neuroradiology. Journal de neuroradiologie     Volume:  30     ISSN:  0150-9861     ISO Abbreviation:  J Neuroradiol     Publication Date:  2003 Mar 
Date Detail:
Created Date:  2003-04-28     Completed Date:  2003-08-05     Revised Date:  2008-02-20    
Medline Journal Info:
Nlm Unique ID:  7705086     Medline TA:  J Neuroradiol     Country:  France    
Other Details:
Languages:  eng     Pagination:  121-6     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery, Mohammed V Military Hospital, Rabat, Morocco. akhaddar@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Cerebellar Neoplasms / diagnosis*,  pathology,  radiotherapy,  surgery
Cerebellum / pathology,  surgery
Combined Modality Therapy
Female
Humans
Hydrocephalus / diagnosis,  pathology,  surgery
Magnetic Resonance Imaging*
Medulloblastoma / diagnosis*,  pathology,  radiotherapy,  surgery
Neurologic Examination*
Prognosis
Radiotherapy, Adjuvant
Tomography, X-Ray Computed*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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