Document Detail

Cerebellar growth in normal fetuses of multiple gestations.
MedLine Citation:
PMID:  12380675     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this study was to compare the cerebellar growth in twin and triplet gestations with cerebellar growth in singleton pregnancies. METHODOLOGY: An ultrasound study was conducted in a population of normal pregnant women with singleton, twin and triplet gestations. Routine ultrasound examinations were performed in healthy pregnant women: 951 women with singleton pregnancies; 151 with twin gestations; and 28 with triplet gestations. Although multiple biometric parameters were measured throughout the course of pregnancy, in this study a single measurement (the last measurement before delivery) of the transverse cerebellar diameter (TCD) was used from each patient for statistical analysis. Growth of the TCD was determined in the multiple gestations and compared with growth in singleton pregnancies. RESULTS: A statistically significant relationship was found between TCD and gestational age in all three groups (singleton, twin A and B, and triplets) respectively: R2 = 0.963; R2 = 0.980; R2 = 0.977. No statistical difference was found between the three sets of normative measurements. CONCLUSIONS: There was no significant difference observed in cerebellar growth among singleton and multiple gestations. Therefore, nomograms previously established for singleton pregnancies may be useful to assess growth in multifetal pregnancies.
I Goldstein; E A Reece; A Tamir
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  11     ISSN:  1476-7058     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2002 Mar 
Date Detail:
Created Date:  2002-10-16     Completed Date:  2003-01-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  188-91     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Rambam Medical Center, Haifa, Israel.
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MeSH Terms
Case-Control Studies
Cerebellum / embryology*,  ultrasonography
Cross-Sectional Studies
Gestational Age
Linear Models
Pregnancy, Multiple*
Prospective Studies
Reference Values
Ultrasonography, Prenatal

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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