Document Detail


Cerebellar defect associated with Schimke immuno-osseous dysplasia.
MedLine Citation:
PMID:  11421418     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report the finding of an absent cerebellar hemisphere and partial absence of the cerebellar vermis in a child with dysmorphic features, spondyloepiphyseal dysplasia, steroid resistant nephrotic syndrome secondary to focal segmental glomerulosclerosis and T-cell lymphopenia (Schimke immuno-osseous dysplasia). These findings have not, to our knowledge, been described before and are likely to represent the consequence of a vascular event either in-utero or in early infancy. CONCLUSION: Cerebral imaging should be performed early in the course of the disease and should be repeated if further neurological events develop.
Authors:
A S Dhillon; S Chapman; D V Milford
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European journal of pediatrics     Volume:  160     ISSN:  0340-6199     ISO Abbreviation:  Eur. J. Pediatr.     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2001-06-25     Completed Date:  2001-11-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7603873     Medline TA:  Eur J Pediatr     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  372-4     Citation Subset:  IM    
Affiliation:
Department of Nephrology, Birmingham Children's Hospital NHS Trust, UK.
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MeSH Terms
Descriptor/Qualifier:
Cerebellum / pathology*
Female
Humans
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / pathology*
Magnetic Resonance Imaging
Osteochondrodysplasias / pathology*
Syndrome

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