Document Detail

Cephalic phase response of pancreatic exocrine secretion in conscious dogs.
MedLine Citation:
PMID:  3348407     Owner:  NLM     Status:  MEDLINE    
The effects of three taste solutions on the cephalic phase of pancreatic secretion were studied in conscious dogs. Male beagle dogs weighing 9-11 kg were prepared with gastric and duodenal fistulas. Gustatory receptors were stimulated for 5 min with 100 ml of 0.5% agar solutions containing 0.05, 0.12, and 0.3 M of either sodium chloride, sucrose, or monosodium glutamate (MSG). Pancreatic juice was collected every 5 min before and after stimulation, and volume flow and protein output were measured. Pancreatic secretory responses were found to vary with the type of taste stimulus. Sucrose was a better stimulus than MSG for both protein output and volume flow. Taste stimulation with sodium chloride produced a lower pancreatic response than those with sucrose or MSG.
I Ohara; S Otsuka; Y Yugari
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of physiology     Volume:  254     ISSN:  0002-9513     ISO Abbreviation:  Am. J. Physiol.     Publication Date:  1988 Mar 
Date Detail:
Created Date:  1988-04-21     Completed Date:  1988-04-21     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0370511     Medline TA:  Am J Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  G424-8     Citation Subset:  IM    
Life Science Laboratory, Central Research Laboratories, Ajinomoto Company, Yokohama, Japan.
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MeSH Terms
Pancreas / metabolism,  secretion*
Proteins / metabolism
Sodium Chloride / pharmacology
Sodium Glutamate / pharmacology
Stimulation, Chemical
Sucrose / pharmacology
Taste / physiology*
Reg. No./Substance:
0/Proteins; 142-47-2/Sodium Glutamate; 57-50-1/Sucrose; 7647-14-5/Sodium Chloride

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