| Centrosomes and mitotic poles. | |
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MedLine Citation:
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PMID: 6734733 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The original theory of the centrosome as the 'reproductive organ' of the cell provides a logical explanation of the mitotic poles and the accuracy of cell division. No alternative explanation has replaced it. The historical problem was the failure to identify centrosomes as compact physical bodies in a great many kinds of cells. In this essay, I consider the evidence that centrosomes are flexible bodies; they may take on alternative forms and their forms determine the shapes of mitotic poles and other organizers of microtubular structures. Compact corpuscular centrosomes are not necessary and would not be expected in cases where microtubules clearly do not originate from point sources. A model of the flexible centrosome is introduced and the speculation that the centrosome is a bearer of morphological information is considered. |
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Authors:
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D Mazia |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Experimental cell research Volume: 153 ISSN: 0014-4827 ISO Abbreviation: Exp. Cell Res. Publication Date: 1984 Jul |
Date Detail:
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Created Date: 1984-08-01 Completed Date: 1984-08-01 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0373226 Medline TA: Exp Cell Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1-15 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cell Cycle Cell Nucleus / physiology Centrioles / ultrastructure Female Fertilization Male Mitosis* Models, Genetic Organoids / physiology* Ovum / physiology Plants / genetics |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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