| Central venous pressure in humans during microgravity. | |
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MedLine Citation:
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PMID: 8828692 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Based on the results of head-down simulation studies and the results of parabolic flights, the hypothesis was tested that central venous pressure (CVP) in humans increases during microgravity (weightlessness) compared with during the ground-based supine position. CVP was recorded with an intravascular pressure transducer in seven healthy humans during short (20-s) periods of microgravity created by parabolic-flight maneuvers and in one astronaut before, during, and up to 3 h after launch of the Spacelab D-2 mission (Space Transport System-55). When the subjects were supine during the parabolic maneuver, CVP decreased during microgravity from 6.5 +/- 1.3 to 5.0 +/- 1.4 mmHg (P < 0.05). during the Spacelab D-2 mission, CVP was 6.2 mmHg during the initial minutes of microgravity, which was very similar to the value of 6.5 mmHg in the supine position 3.5 h before launch of the space shuttle. During the subsequent 3 h of weightlessness, CVP during rest varied between 2.0 and 6.2 mmHg. We conclude that CVP during short (20-s) and longer (3-h) periods of microgravity is close to or below that of the supine position on the ground. |
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Authors:
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N Foldager; T A Andersen; F B Jessen; P Ellegaard; C Stadeager; R Videbaek; P Norsk |
Publication Detail:
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Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of applied physiology (Bethesda, Md. : 1985) Volume: 81 ISSN: 8750-7587 ISO Abbreviation: J. Appl. Physiol. Publication Date: 1996 Jul |
Date Detail:
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Created Date: 1996-12-18 Completed Date: 1996-12-18 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8502536 Medline TA: J Appl Physiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 408-12 Citation Subset: IM; S |
Affiliation:
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Danish Aerospace Medical Centre of Research, Rigshospitalet, Copenhagen, Denmark. |
Space Flight Mission:
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Flight Experiment; Parabolic Flight; STS-55 Shuttle Project; manned; short duration |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Central Venous Pressure / physiology* Female Heart Rate / physiology Humans Male Middle Aged Space Flight Supine Position / physiology Weightlessness / adverse effects* Weightlessness Simulation |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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