| Central venous oxygen saturation for the diagnosis of low cardiac output in septic shock patients. | |
| | |
MedLine Citation:
|
PMID: 19735495 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Simple diagnostic tests are needed to screen septic patients for low cardiac output because intervention is recommended in these patients. We assessed the diagnostic value of central venous oxygen saturation in the superior vena cava (ScvO(2)) for detecting low cardiac output in patients with septic shock. METHODS: We conducted a prospective observational study in three general intensive care units (ICUs) of adult patients with septic shock, who were to have a catheter inserted for thermodilution measurement of cardiac index (CI(TD)). Paired measurements of CI(TD) and central venous oximetry values were obtained when the clinician first measured CI(TD). RESULTS: We included 56 patients with septic shock and a mean sequential organ failure assessment score of 12 (range 3-20). Baseline CI(TD) was 3.5 l/min/m(2) (1.0-6.2) and ScvO(2) of 70% (33-87). The best cut-off of ScvO(2) for CI(TD)>2.5 l/min/m(2) (n=42) was a value >or=64% with positive and negative predictive values of 91% (95% confidence interval 79-98) and 91% (59-100), respectively. The diagnostic values were not improved by using instead central venous O(2) tension or the difference between arterial and central venous O(2) saturation. CONCLUSIONS: This prospective, observational study found that a ScvO(2) measurement of >or=64% indicated CI(TD)>2.5 l/min/m(2) in ICU patients with septic shock. |
| | |
Authors:
|
A Perner; N Haase; J Wiis; J O White; A Delaney |
Related Documents
:
|
3126305 - Factors influencing energy expenditure in patients with burns. 18571985 - Percutaneous coronary intervention for acute mi does not prevent in-hospital developmen... 2417455 - Developments in the resuscitation of critically ill surgical patients. 2719205 - Pulse oximetry in methaemoglobinaemia. failure to detect low oxygen saturation. 12050605 - Comparison of echocardiographic markers of right ventricular function in determining pr... 8881865 - Is the clinical spectrum and prognosis of native valve infective endocarditis in non-ad... |
Publication Detail:
|
Type: Journal Article Date: 2009-09-07 |
Journal Detail:
|
Title: Acta anaesthesiologica Scandinavica Volume: 54 ISSN: 1399-6576 ISO Abbreviation: Acta Anaesthesiol Scand Publication Date: 2010 Jan |
Date Detail:
|
Created Date: 2009-12-07 Completed Date: 2010-02-22 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0370270 Medline TA: Acta Anaesthesiol Scand Country: England |
Other Details:
|
Languages: eng Pagination: 98-102 Citation Subset: IM |
Affiliation:
|
Department of Intensive Care, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. anders.perner@rh.regionh.dk |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Cardiac Output, Low / diagnosis* Catheterization, Central Venous Humans Oximetry / methods* Oxygen / blood* Predictive Value of Tests Prospective Studies Shock, Septic / physiopathology* Vena Cava, Superior Young Adult |
| Chemical | |
Reg. No./Substance:
|
7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Single stimulation of the posterior cord is superior to dual nerve stimulation in a coracoid block.
Next Document: Early high C-reactive protein in infants with open abdominal wall defects does not predict sepsis or...