| Central venous lines for chronic hemodialysis: survey of the Midwest Pediatric Nephrology Consortium. | |
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MedLine Citation:
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PMID: 18008090 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Central venous lines (CVL) continue to be the most commonly used vascular access device for children on hemodialysis (HD). Despite their frequent use, little is known regarding the frequency of CVL-related intradialytic complications that could interfere with delivery of effective dialysis. To better assess this, we conducted a cross-sectional study of ten HD centers within the Midwest Pediatric Nephrology Consortium. Vascular access was provided by CVL in 61 of the 83 patients (73%) included. CVL dysfunction (defined as reduced blood flows, need for reversed lines, or frequent intradialytic alarms) occurred in 46% in the prior month. Treatment for suspected clots occurred in 16 patients. Intraluminal tissue plasminogen activator (tPA) was the preferred treatment for a suspected clot. The survey also inquired about the preferred treatment for documented clots, and intraluminal tPA was most preferred, followed by CVL stripping, CVL removal, CVL brushing, and systemic tPA. As for preventative strategies, most HD centers locked the CVL with intraluminal heparin in concentrations ranging from 1,000 to 5,000 U/ml. In conclusion, catheter usage rates and complications were highly prevalent in pediatric HD units in this study. As treatment strategies varied greatly, future prospective studies are needed to determine the effectiveness of each individual therapy. |
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Authors:
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Rudolph P Valentini; Denis F Geary; Deepa H Chand |
Publication Detail:
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Type: Journal Article; Multicenter Study Date: 2007-11-16 |
Journal Detail:
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Title: Pediatric nephrology (Berlin, Germany) Volume: 23 ISSN: 0931-041X ISO Abbreviation: Pediatr. Nephrol. Publication Date: 2008 Feb |
Date Detail:
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Created Date: 2008-01-14 Completed Date: 2008-06-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8708728 Medline TA: Pediatr Nephrol Country: Germany |
Other Details:
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Languages: eng Pagination: 291-5 Citation Subset: IM |
Affiliation:
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Division of Nephrology, The Carman and Ann Adams Department of Pediatrics, Children's Hospital of Michigan, Wayne State University School of Medicine, Detroit, MI, USA. rvalen@med.wayne.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Catheterization, Central Venous
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adverse effects,
instrumentation*,
statistics & numerical data Catheters, Indwelling / adverse effects, statistics & numerical data Cross-Sectional Studies Equipment Failure / statistics & numerical data Health Care Surveys* Humans Kidney Failure, Chronic / complications, therapy* Nephrology / methods* Questionnaires Renal Dialysis / instrumentation*, statistics & numerical data |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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