Document Detail

Central venous catheter thrombosis as a cause of SVC obstruction and cardiac tamponade in a patient with Diamond-Blackfan anemia and iron overload.
MedLine Citation:
PMID:  15768384     Owner:  NLM     Status:  MEDLINE    
Cardiac tamponade is an infrequent but potentially lethal complication related to use of central venous catheters (CVC). We present the case of a 16-year-old female with Diamond-Blackfan anemia (DBA) who developed pericardial tamponade secondary to superior venous caval obstruction caused by CVC thrombosis. The patient presented 3 months after line placement with vomiting, abdominal pain, and cardiomegaly on chest X-ray (CXR). Her condition quickly decompensated with cardiac arrest and subsequent death despite immediate pericardiocentesis. As a result of this case, our center has developed a protocol for the management of CVC problems as a means of facilitating rapid recognition of central line clots.
Mark L Norris; Robert Klaassen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric blood & cancer     Volume:  46     ISSN:  1545-5009     ISO Abbreviation:  Pediatr Blood Cancer     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2005-11-22     Completed Date:  2006-02-16     Revised Date:  2009-01-12    
Medline Journal Info:
Nlm Unique ID:  101186624     Medline TA:  Pediatr Blood Cancer     Country:  United States    
Other Details:
Languages:  eng     Pagination:  112-4     Citation Subset:  IM    
Department of Pediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.
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MeSH Terms
Anemia, Diamond-Blackfan / therapy*
Cardiac Tamponade / etiology*
Catheterization, Central Venous / adverse effects*
Fatal Outcome
Iron Overload / therapy*
Superior Vena Cava Syndrome / etiology*

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