Document Detail

Central serous chorioretinopathy associated with the use of spironolactone, aldosterone receptor antagonist.
MedLine Citation:
PMID:  25389939     Owner:  NLM     Status:  In-Data-Review    
PURPOSE: To report a case of central serous chorioretinopathy caused by the use of spironolactone, a competitive antagonist of aldosterone.
METHODS: Case report and review of the literature.
RESULTS: A 26-year-old white woman on Aldactone (spironolactone) for the treatment of acne and Adderall (dextroamphetamine/amphetamine) for the treatment of attention deficit hyperactivity disorder, developed central serous chorioretinopathy, which resolved upon discontinuation of spironolactone and remitted after restarting it.
CONCLUSION: It is likely that spironolactone use contributed to the development of central serous chorioretinopathy in this patient. Concomitant use of amphetamine may also have played a role.
Anna Gabrielian; Mathew W MacCumber
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Retinal cases & brief reports     Volume:  6     ISSN:  1935-1089     ISO Abbreviation:  Retin Cases Brief Rep     Publication Date:  2012  
Date Detail:
Created Date:  2014-11-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101298744     Medline TA:  Retin Cases Brief Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  393-5     Citation Subset:  -    
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