| Central prostaglandins in food intake regulation. | |
MedLine Citation:
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PMID: 18662860 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Prostaglandin (PG) E(2) and PGD(2), produced in the mammalian central nervous system, are known to have a variety of central actions on sleep, body temperature, and pain response via G-protein-coupled seven-transmembrane receptors. We found that centrally administered PGE(2) suppressed food intake via the EP(4) receptor, whereas PGD(2) increased food intake via the DP(1) receptor coupled to the neuropeptide Y Y(1) receptor. In this review, we summarize roles of central PGs in food intake regulation and discuss the relation between PGs and neuropeptides controlling food intake. |
Authors:
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Kousaku Ohinata; Masaaki Yoshikawa |
Publication Detail:
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Type: Journal Article; Review Date: 2008-07-26 |
Journal Detail:
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Title: Nutrition (Burbank, Los Angeles County, Calif.) Volume: 24 ISSN: 0899-9007 ISO Abbreviation: Nutrition Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-08-26 Completed Date: 2009-01-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8802712 Medline TA: Nutrition Country: United States |
Other Details:
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Languages: eng Pagination: 798-801 Citation Subset: IM |
Affiliation:
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Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Kyoto, Japan. ohinata@kais.kyoto-u.ac.jp |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Appetite Regulation / physiology Eating / physiology* Feeding Behavior / physiology* Humans Hypothalamus / metabolism Mice Neuropeptides / metabolism, pharmacology Prostaglandins / chemistry, metabolism*, pharmacology* |
| Chemical | |
Reg. No./Substance:
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0/Neuropeptides; 0/Prostaglandins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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