Document Detail

Central precocious puberty due to hypothalamic hamartoma in a 7-month-old infant girl.
MedLine Citation:
PMID:  17541635     Owner:  NLM     Status:  MEDLINE    
Hypothalamic hamartomas (HH) are rare congenital lesions of the tuber cinereum presenting with the classic triad of gelastic epilepsy, central precocious puberty (CPP) and developmental delay. In light of the important and diverse consequences of precocious puberty for affected children and their families, a correct diagnosis without delay is imperative. We present here a rare case of a 7-month-old infant girl with CPP and HH who was successfully treated with depot gonadotropin-releasing hormone (GnRH) analogue is presented.
I H Rousso; M Kourti; D Papandreou; A Tragiannidis; F Athanasiadou
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-06-01
Journal Detail:
Title:  European journal of pediatrics     Volume:  167     ISSN:  0340-6199     ISO Abbreviation:  Eur. J. Pediatr.     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-03-19     Completed Date:  2008-08-21     Revised Date:  2010-08-12    
Medline Journal Info:
Nlm Unique ID:  7603873     Medline TA:  Eur J Pediatr     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  583-5     Citation Subset:  IM    
2nd Department of Pediatrics, Aristotle University of Thessaloniki, Thessaloniki, Greece.
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MeSH Terms
Delayed-Action Preparations
Estradiol / blood
Follow-Up Studies
Gonadotropin-Releasing Hormone / analogs & derivatives
Hamartoma / complications*,  diagnosis
Hypothalamic Diseases / complications*,  diagnosis
Injections, Intramuscular
Luteinizing Hormone / blood
Luteolytic Agents / administration & dosage
Magnetic Resonance Imaging
Puberty, Precocious / blood,  drug therapy,  etiology*
Triptorelin / administration & dosage
Reg. No./Substance:
0/Delayed-Action Preparations; 0/Luteolytic Agents; 33515-09-2/Gonadotropin-Releasing Hormone; 50-28-2/Estradiol; 57773-63-4/Triptorelin; 9002-67-9/Luteinizing Hormone

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