Document Detail

Central pontine myelinolysis central pontine myelinolysis manifesting with massive myoclonus.
MedLine Citation:
PMID:  15246496     Owner:  NLM     Status:  MEDLINE    
Central pontine myelinolysis is a rare neurologic disorder defined by symmetric demyelination in the central base of the pons. It usually manifests with neurologic signs such as impaired consciousness, ataxia, spastic quadriparesis, pseudobulbar signs, and the locked-in syndrome which is related to a disconnection syndrome at the pontine level. We report a 17-month-old patient with kwashiorkor and hyponatremia who developed acute massive myoclonus. Magnetic resonance imaging revealed a central pontine lesion. Central pontine myelinolysis is rare in infants, with only a few cases reported in the literature so far. This report presents the first infantile case of central pontine myelinolysis manifesting with massive myoclonus.
Hüseyin Tan; Omer Onbaş
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric neurology     Volume:  31     ISSN:  0887-8994     ISO Abbreviation:  Pediatr. Neurol.     Publication Date:  2004 Jul 
Date Detail:
Created Date:  2004-07-12     Completed Date:  2004-09-24     Revised Date:  2006-05-23    
Medline Journal Info:
Nlm Unique ID:  8508183     Medline TA:  Pediatr Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  64-6     Citation Subset:  IM    
Department of Pediatric Neurology, Erzurum, Turkey.
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MeSH Terms
Hyponatremia / complications
Kwashiorkor / complications
Magnetic Resonance Imaging
Myelinolysis, Central Pontine / complications*,  pathology*
Myoclonus / etiology*,  pathology*

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