| Central neurocytoma: clinico-pathological study of 5 cases and review of the literature. | |
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MedLine Citation:
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PMID: 7586853 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Five cases of central neurocytoma, confirmed by immunohistochemical and electron microscopy studies, are reported and 127 cases from the literature are reviewed. Central neurocytomas are more frequent than previously thought, and will be diagnosed with increasing frequency in the future, if intraventricular tumors with histological aspect of oligodendroglioma or ependymoma will be routinely studied by immunohistochemistry and electron microscopy. The occurrence of an intraventricular tumor with a typical MR aspect in a young patient should suggest preoperatively the diagnosis of neurocytoma. The positivity for synaptophysin and neuron specific enolase, the negativity for neurofilament protein and glial fibrillary acid protein, and the finding of elements of neuronal differentiation on electron microscopy, are the main pathological features of these tumors. Complete removal of the tumor mass without radiotherapy is the treatment of choice. The prognosis is usually favorable without recurrence. |
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Authors:
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F Maiuri; R Spaziante; M L De Caro; P Cappabianca; A Giamundo; G Iaconetta |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Clinical neurology and neurosurgery Volume: 97 ISSN: 0303-8467 ISO Abbreviation: Clin Neurol Neurosurg Publication Date: 1995 Aug |
Date Detail:
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Created Date: 1995-12-28 Completed Date: 1995-12-28 Revised Date: 2009-10-14 |
Medline Journal Info:
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Nlm Unique ID: 7502039 Medline TA: Clin Neurol Neurosurg Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 219-28 Citation Subset: IM |
Affiliation:
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Department of Neurosurgery and Pathology, School of Medicine, University Federico II, Naples, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Brain Neoplasms / diagnosis, pathology*, surgery Cerebral Ventricle Neoplasms / diagnosis, pathology, surgery Diagnosis, Differential Ependymoma / diagnosis, pathology, surgery Female Follow-Up Studies Humans Immunoenzyme Techniques Magnetic Resonance Imaging Male Microscopy, Electron Neurocytoma / diagnosis, pathology*, surgery Oligodendroglioma / diagnosis, pathology, surgery Phosphopyruvate Hydratase / analysis Synaptophysin / analysis Tumor Markers, Biological / analysis |
| Chemical | |
Reg. No./Substance:
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0/Synaptophysin; 0/Tumor Markers, Biological; EC 4.2.1.11/Phosphopyruvate Hydratase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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