Document Detail


Central neurocytoma: clinico-pathological study of 5 cases and review of the literature.
MedLine Citation:
PMID:  7586853     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Five cases of central neurocytoma, confirmed by immunohistochemical and electron microscopy studies, are reported and 127 cases from the literature are reviewed. Central neurocytomas are more frequent than previously thought, and will be diagnosed with increasing frequency in the future, if intraventricular tumors with histological aspect of oligodendroglioma or ependymoma will be routinely studied by immunohistochemistry and electron microscopy. The occurrence of an intraventricular tumor with a typical MR aspect in a young patient should suggest preoperatively the diagnosis of neurocytoma. The positivity for synaptophysin and neuron specific enolase, the negativity for neurofilament protein and glial fibrillary acid protein, and the finding of elements of neuronal differentiation on electron microscopy, are the main pathological features of these tumors. Complete removal of the tumor mass without radiotherapy is the treatment of choice. The prognosis is usually favorable without recurrence.
Authors:
F Maiuri; R Spaziante; M L De Caro; P Cappabianca; A Giamundo; G Iaconetta
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Clinical neurology and neurosurgery     Volume:  97     ISSN:  0303-8467     ISO Abbreviation:  Clin Neurol Neurosurg     Publication Date:  1995 Aug 
Date Detail:
Created Date:  1995-12-28     Completed Date:  1995-12-28     Revised Date:  2009-10-14    
Medline Journal Info:
Nlm Unique ID:  7502039     Medline TA:  Clin Neurol Neurosurg     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  219-28     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery and Pathology, School of Medicine, University Federico II, Naples, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adult
Brain Neoplasms / diagnosis,  pathology*,  surgery
Cerebral Ventricle Neoplasms / diagnosis,  pathology,  surgery
Diagnosis, Differential
Ependymoma / diagnosis,  pathology,  surgery
Female
Follow-Up Studies
Humans
Immunoenzyme Techniques
Magnetic Resonance Imaging
Male
Microscopy, Electron
Neurocytoma / diagnosis,  pathology*,  surgery
Oligodendroglioma / diagnosis,  pathology,  surgery
Phosphopyruvate Hydratase / analysis
Synaptophysin / analysis
Tumor Markers, Biological / analysis
Chemical
Reg. No./Substance:
0/Synaptophysin; 0/Tumor Markers, Biological; EC 4.2.1.11/Phosphopyruvate Hydratase

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