Document Detail


Central nervous system norepinephrine metabolism in hypertension.
MedLine Citation:
PMID:  10981164     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Although the pivotal role played by the brain in the maintenance of optimal physiologic and psychologic health has long been recognized, methods for the direct examination of human central nervous system processes have only recently been developed. A growing body of evidence indicates that central nervous systemmonoaminergic cell groups, in particular those utilizing norepinephrine as their neurotransmitter, participate in the excitatory regulation of the sympathetic nervous system and the development of the hypertensive state.
Authors:
G W Lambert
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Current hypertension reports     Volume:  2     ISSN:  1522-6417     ISO Abbreviation:  Curr. Hypertens. Rep.     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2000-10-13     Completed Date:  2000-10-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100888982     Medline TA:  Curr Hypertens Rep     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  302-10     Citation Subset:  IM    
Affiliation:
Human Neurotransmitters Laboratory, Baker Medical Research Institute, PO Box 6492, St. Kilda Road Central, Melbourne, Victoria 8008, Australia. gavin@baker.edu.au
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MeSH Terms
Descriptor/Qualifier:
Adrenergic alpha-Agonists / metabolism*
Brain / metabolism*,  physiopathology
Humans
Hypertension / metabolism*,  physiopathology
Neurotransmitter Agents / metabolism,  physiology
Norepinephrine / metabolism*
Sympathetic Nervous System / metabolism,  physiopathology
Sympathomimetics / metabolism*
Chemical
Reg. No./Substance:
0/Adrenergic alpha-Agonists; 0/Neurotransmitter Agents; 0/Sympathomimetics; 51-41-2/Norepinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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