| Central nervous system medication changes and falls in nursing home residents. | |
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MedLine Citation:
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PMID: 19818269 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We investigated the role of changes in 6 mutually exclusive medication categories on the risk of falling in nursing home residents. The 6 categories were: gastrointestinal, hypoglycemics, antibiotics, central nervous system (CNS) acting, cardiovascular disease agents, and analgesics. A change was defined as a new start, a dose change, an as-needed dose, or a discontinuation. Incident reports were used to determine the fall date and time. Medication records were abstracted to identify the date of changes before the date of each fall. The 158 residents who fell had 419 recorded falls during 2002 and 2003; they were on average 80.5 years old (SD 8.1; range 65-103), and 67% were men. Within 1-3 days of a change in any CNS medication (antipsychotic, sedative, antidepressant, or antiseizure), the fall risk (odds ratio) increased 3.4-fold (95% confidence interval 1.2-9.5) using 7-9 days prior as comparable control days. No changes in other medication categories had a significant effect on fall risk. These data suggest that the risk of falls among nursing home residents is significantly elevated within 3 days of a CNS medication change. |
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Authors:
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Gary S Sorock; Patricia A Quigley; Michelle K Rutledge; Jennifer Taylor; Xianghua Luo; Philip Foulis; Mei-Cheng Wang; Ravi Varadhan; Michele Bellantoni; Susan P Baker |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Geriatric nursing (New York, N.Y.) Volume: 30 ISSN: 1528-3984 ISO Abbreviation: Geriatr Nurs Publication Date: 2009 Sep-Oct |
Date Detail:
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Created Date: 2009-10-12 Completed Date: 2009-12-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8309633 Medline TA: Geriatr Nurs Country: United States |
Other Details:
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Languages: eng Pagination: 334-40 Citation Subset: N |
Affiliation:
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Geriatric Research Services, Glyndon, MD, USA. gsoro001@umaryland.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Accidental Falls* Aged Aged, 80 and over Central Nervous System / drug effects*, physiopathology Cross-Over Studies Female Humans Inpatients* Male Nursing Homes* |
| Grant Support | |
ID/Acronym/Agency:
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H400-888-2152//PHS HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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