Document Detail

Central nervous system complications in patients with bacteremia.
MedLine Citation:
PMID:  2667096     Owner:  NLM     Status:  MEDLINE    
The occurrence of central nervous system (CNS) complications was studied retrospectively in 150 patients with bacteremia caused by Staphylococcus aureus, Streptococcus pneumoniae, beta-hemolytic streptococci or Escherichia coli. The incidence and clinical manifestations of different CNS complications were noted during 1 month after the bacteremia. Special attention was paid to vascular complications (infarction or hemorrhage), infections (meningitis or brain abscess) and mental changes when they were the only signs of CNS origin (lowered level of consciousness, confusion or delirium). The risk of cerebral infarction was elevated in the patients with bacteremia during the first month after the positive blood culture as compared with the overall risk of stroke in the general population. 10/150 patients (7%) developed cerebral infarction during that month. Two of these cases were associated with bacterial meningitis and 1 with endocarditis. Mental changes as a main symptom of CNS origin occurred in 27% of patients with bacteremia. Increasing patient age predisposed to this complication. Mental changes were not associated with any bacterial species studied. Altogether 40% of the patients developed CNS complications, which were a significant risk factor for death during the first month after the bacteremia.
J Syrjänen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian journal of infectious diseases     Volume:  21     ISSN:  0036-5548     ISO Abbreviation:  Scand. J. Infect. Dis.     Publication Date:  1989  
Date Detail:
Created Date:  1989-08-29     Completed Date:  1989-08-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0215333     Medline TA:  Scand J Infect Dis     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  285-96     Citation Subset:  IM    
Department of Bacteriology and Immunology, University of Helsinki, Finland.
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MeSH Terms
Age Factors
Aged, 80 and over
Brain Diseases / epidemiology,  etiology*
Escherichia coli Infections / complications*
Follow-Up Studies
Mental Disorders / epidemiology,  etiology
Middle Aged
Retrospective Studies
Sepsis / complications*
Staphylococcal Infections / complications*
Streptococcal Infections / complications*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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