Document Detail


Central mechanisms of roles of taste in reward and eating.
MedLine Citation:
PMID:  18642757     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Taste is unique among sensory systems in its innate association with mechanisms of reward and aversion in addition to its recognition of quality, e.g., sucrose is sweet and preferable, and quinine is bitter and aversive. Taste information is sent to the reward system and feeding center via the prefrontal cortices such as the mediodorsal and ventrolateral prefrontal cortices in rodents and the orbitofrontal cortex in primates. The amygdala, which receives taste inputs, also influences reward and feeding. In terms of neuroactive substances, palatability is closely related to benzodiazepine derivatives and beta-endorphin, both of which facilitate consumption of food and fluid. The reward system contains the ventral tegmental area, nucleus accumbens and ventral pallidum and finally sends information to the lateral hypothalamic area, the feeding center. The dopaminergic system originating from the ventral tegmental area mediates the motivation to consume palatable food. The actual ingestive behavior is promoted by the orexigenic neuropeptides from the hypothalamus. Even palatable food can become aversive and avoided as a consequence of a postingestional unpleasant experience such as malaise. The neural mechanisms of this conditioned taste aversion will also be elucidated.
Authors:
T Yamamoto
Related Documents :
12449287 - Children's food preferences: a longitudinal analysis.
21036327 - Genetics of taste and smell: poisons and pleasures.
22624447 - Oral immunotherapy for the treatment of food allergy.
9744207 - Palatability versus healthiness as determinants of food preferences in young adults: a ...
18320157 - Ethanol concentration in food and body condition affect foraging behavior in egyptian f...
22376987 - Associations of home food availability, dietary intake, screen time and physical activi...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Acta physiologica Hungarica     Volume:  95     ISSN:  0231-424X     ISO Abbreviation:  Acta Physiol Hung     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-07-22     Completed Date:  2008-09-02     Revised Date:  2014-03-25    
Medline Journal Info:
Nlm Unique ID:  8309201     Medline TA:  Acta Physiol Hung     Country:  Hungary    
Other Details:
Languages:  eng     Pagination:  165-86     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Cerebrum / physiology*
Eating / physiology,  psychology*
Feeding Behavior / physiology,  psychology*
Humans
Reward*
Taste / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Functions of the orbitofrontal and pregenual cingulate cortex in taste, olfaction, appetite and emot...
Next Document:  Does selenium exert cardioprotective effects against oxidative stress in myocardial ischemia?