| Central haemodynamics in acute myocardial infarction in relation to mortality and peak enzyme activity. | |
| | |
MedLine Citation:
|
PMID: 3732297 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The relation of central haemodynamic changes to subsequent mortality and peak enzyme activity was investigated in 190 patients with acute myocardial infarction. The mean delay time from onset of symptoms to the haemodynamic study was 7.2 hours. Major exclusion criteria were heart rate less than 65 beats min-1, systolic blood pressure less than 105 mmHg and lung rales to a distance of greater than 10 cm above the lung bases. Nine patients (4.7%) died within 15 days and 16 patients (8.4%) within 90 days after the infarction. Compared to survivors, non-survivors were characterized by baseline depression of cardiac index, stroke volume index and left ventricular stroke work index, while pulmonary capillary wedge pressure and peripheral resistance were increased. However, a wide overlap between survivors and non-survivors makes the predictive value low in the individual patient. Peak serum aspartate aminotransferase (S-ASAT) activity was weakly related to baseline pulmonary capillary wedge pressure (r = 0.28; P less than 0.001) and stroke volume index (r = -0.22; P less than 0.01). The correlation to pulmonary capillary wedge pressure was only found in anterior (r = 0.34) infarcts. Peak serum lactate dehydrogenase (LD1) was not correlated with baseline haemodynamics. |
| | |
Authors:
|
P H Held; H M Corbeij; P Dunselman; A Hjalmarson; D Murray; K Swedberg |
Related Documents
:
|
1638107 - Cardiovascular instability during sleep and calm waking state in normal man. 21371277 - The management of hypertension for primary stroke prevention: a proposed approach. 11590277 - Intracerebral haemorrhage and qigong. 10066867 - Cerebrovascular alterations in protein kinase c-mediated constriction in stroke-prone r... 7735987 - High volume hemofiltration improves hemodynamics and survival of pigs exposed to gut is... 14525107 - Similarity scaling of pressure fluctuation in turbulence. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: European heart journal Volume: 7 ISSN: 0195-668X ISO Abbreviation: Eur. Heart J. Publication Date: 1986 Jun |
Date Detail:
|
Created Date: 1986-09-17 Completed Date: 1986-09-17 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8006263 Medline TA: Eur Heart J Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 475-81 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Aspartate Aminotransferases / blood Cardiac Output Female Heart Rate Heart Ventricles / physiopathology Hemodynamics* Humans L-Lactate Dehydrogenase / blood Male Middle Aged Myocardial Infarction / enzymology, mortality, physiopathology* Myocardium / pathology Prognosis Pulmonary Wedge Pressure Stroke Volume |
| Chemical | |
Reg. No./Substance:
|
EC 1.1.1.27/L-Lactate Dehydrogenase; EC 2.6.1.1/Aspartate Aminotransferases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Bacterial endocarditis of the aortic valve with septic coronary embolism and myocardial infarction i...
Next Document: Simultaneous measurement of left ventricular function and myocardial perfusion during a single exerc...