Document Detail

Central corneal thickness in patients with mild to moderate rosacea.
MedLine Citation:
PMID:  23217504     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVE: We aimed to evaluate central corneal thickness (CCT) in patients with rosacea in comparison to a healthy control group and to investigate any correlations by using the Schirmer test, tear break-up time (TBUT), and disease severity.
DESIGN: Prospective nonrandomized study.
PARTICIPANTS: Patients with mild to moderate rosacea (n = 51) and a group of healthy individuals (n = 51) were included.
METHOD: Patients were evaluated by a dermatologist; disease severity was determined and total rosacea severity score was calculated for each patient. CCT measurements were performed using ultrasonic pachymetry. Tear function tests, including Schirmer and TBUT, were also performed.
RESULTS: The mean CCT value was significantly lower in patients with rosacea than in the control group (544.91 ± 29.41 μm vs 559.40 ± 24.18 μm, p = 0.003). The mean Schirmer test value was significantly lower in patients than in controls (10.54 ± 6.09 mm vs 19.13 ± 4.24 mm, p < 0.0001), and the mean TBUT was shorter in the group with rosacea than in the controls (8.32 ± 3.50 s vs 16.67 ± 5.76 s, p < 0.0001). CCT values were found to be correlated with the Schirmer test values in the rosacea group (r = 0.33, p = 0.01).
CONCLUSIONS: Patients with rosacea have thinner corneas, which could be attributed to the observed deteriorated tear function parameters. Candidates for corneal photoablation surgery should be evaluated regarding rosacea disease because the postoperative period could be complicated by decreased ocular wetting and corneal thinning, even in overlooked mild forms.
Zafer Onaran; Ayşe Anıl Karabulut; Gülşah Usta; Kemal Ornek
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie     Volume:  47     ISSN:  0008-4182     ISO Abbreviation:  Can. J. Ophthalmol.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0045312     Medline TA:  Can J Ophthalmol     Country:  England    
Other Details:
Languages:  eng     Pagination:  504-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.
Department of Ophthalmology, Kırıkkale University School of Medicine, Kırıkkale, Turkey. Electronic address:
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