Document Detail

Central cancellation of self-produced tickle sensation.
MedLine Citation:
PMID:  10196573     Owner:  NLM     Status:  MEDLINE    
A self-produced tactile stimulus is perceived as less ticklish than the same stimulus generated externally. We used fMRI to examine neural responses when subjects experienced a tactile stimulus that was either self-produced or externally produced. More activity was found in somatosensory cortex when the stimulus was externally produced. In the cerebellum, less activity was associated with a movement that generated a tactile stimulus than with a movement that did not. This difference suggests that the cerebellum is involved in predicting the specific sensory consequences of movements, providing the signal that is used to cancel the sensory response to self-generated stimulation.
S J Blakemore; D M Wolpert; C D Frith
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Nature neuroscience     Volume:  1     ISSN:  1097-6256     ISO Abbreviation:  Nat. Neurosci.     Publication Date:  1998 Nov 
Date Detail:
Created Date:  1999-04-29     Completed Date:  1999-04-29     Revised Date:  2009-09-29    
Medline Journal Info:
Nlm Unique ID:  9809671     Medline TA:  Nat Neurosci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  635-40     Citation Subset:  IM    
Wellcome Department of Cognitive Neurology, London, UK.
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MeSH Terms
Brain / physiology*
Brain Mapping
Cerebellum / physiology
Hand / physiology
Movement / physiology
Physical Stimulation
Self Stimulation / physiology*
Somatosensory Cortex / physiology
Touch / physiology*
Grant Support
//Wellcome Trust

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