Document Detail


Central anticholinergic syndrome in anesthetic practice.
MedLine Citation:
PMID:  1024454     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Anticholinergic agents may lead to a syndrome described by Longo as the Central Anticholinergic Syndrome (CAS). Patients with this syndrome exhibit one or more of the following: though impairement, disturbance of recent memory, hallucinations, ataxia, excitement, drowsiness of coma. We have reviewed our use of anticholinergics and tried to correlate it with the occurrence of the above symptomatology and have treated 200 cases in which the CAS was diagnosed with physostigmine salicylate (0.04 mg/kg). We also successfully treated 2 cases of apparently central anticholinergic hyperpyrexia in the same way. We would suggest that physostigmine be included in the armamentarium of every anesthetist to combat anticholinergic poisoning by the wide range of presently used anticholinergic drugs. (Act anaesth. belg., 1976, 27, 45-60).
Authors:
J Rupreht; B Dworacek
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta anaesthesiologica Belgica     Volume:  27     ISSN:  0001-5164     ISO Abbreviation:  Acta Anaesthesiol Belg     Publication Date:  1976  
Date Detail:
Created Date:  1977-05-27     Completed Date:  1977-05-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0421022     Medline TA:  Acta Anaesthesiol Belg     Country:  BELGIUM    
Other Details:
Languages:  eng     Pagination:  45-60     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Anesthesia
Central Nervous System Diseases / chemically induced*,  drug therapy
Child
Child, Preschool
Female
Humans
Male
Middle Aged
Nervous System Diseases / chemically induced,  physiopathology
Parasympathetic Nervous System
Parasympatholytics / adverse effects*
Physostigmine / therapeutic use
Synapses / drug effects*
Chemical
Reg. No./Substance:
0/Parasympatholytics; 57-47-6/Physostigmine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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