Document Detail


Central L-alanine reduces energy expenditure with a hypnotic effect under an acute stressful condition in neonatal chicks.
MedLine Citation:
PMID:  18283412     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Recently, we reported that intracerebroventricular (i.c.v.) injection of L-alanine attenuated the stress response under an acute stressful condition in chicks. However, no information of L-alanine was available for the influence on energy expenditure and changes in the posture under stressful conditions. The purpose of the present study was to clarify whether central L-alanine affects heat production (HP) of neonatal chicks, and whether HP is correlated with the behavior after isolation-induced stress. The i.c.v. injection of L-alanine (0.8 micromol) decreased oxygen consumption, carbon dioxide production and HP shortly after injection. Central L-alanine reduced the posture for active wakefulness, but increased the posture for sitting motionless with head drooped (sleeping posture). The present study demonstrates that central L-alanine decreases energy expenditure and causes a hypnotic effect in chicks exposed to an acute stressful condition.
Authors:
Isao Kurauchi; Haruka Yamane; Yousuke Tsuneyoshi; D Michael Denbow; Mitsuhiro Furuse
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-02-19
Journal Detail:
Title:  Amino acids     Volume:  36     ISSN:  1438-2199     ISO Abbreviation:  Amino Acids     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2009-01-06     Completed Date:  2009-03-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9200312     Medline TA:  Amino Acids     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  131-5     Citation Subset:  IM    
Affiliation:
Laboratory of Advanced Animal and Marine Bioresources, Faculty of Agriculture, Graduate School of Bioresources and Bioenvironmental Sciences, Kyushu University, Fukuoka, 812-8581, Japan.
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MeSH Terms
Descriptor/Qualifier:
Alanine / pharmacology
Animals
Animals, Newborn
Behavior, Animal / drug effects
Chickens / metabolism*
Hypnotics and Sedatives / pharmacology*
Male
Stress, Physiological / drug effects*
Time Factors
Chemical
Reg. No./Substance:
0/Hypnotics and Sedatives; 56-41-7/Alanine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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