| Central Corneal Thickness and Intraocular Pressure in a Nepalese Population: The Bhaktapur Glaucoma Study. | |
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MedLine Citation:
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PMID: 21499121 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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PURPOSE: The purpose of the study was to evaluate the characteristics of central corneal thickness and its association with age, sex, and intraocular pressure in a Nepalese population. PATIENTS AND METHODS: The study design was a cross-sectional, population-based survey. Two thousand three hundred thirty patients aged 40 years and older were examined at Tilganga Institute of Ophthalmology, a tertiary referral eye centre in Kathmandu, Nepal. All patients underwent a complete ophthalmic examination that included measurements of central corneal thickness with an ultrasonic pachymeter and intraocular pressure with a Goldman type applanation tonometer. RESULTS: The main outcome measures were central corneal thickness and intraocular pressure. Mean age of the 2330 patients examined was 51.3 years (SD±9.56). The mean central corneal thickness and mean intraocular pressure was 539.10 μm (SD±33.73) and 13.33 mm Hg (SD±2.26), respectively. Central corneal thickness showed an average decrease of 2.67 μm (95% confidence interval, 2.21-4.1) per decade increase in age. A 100 μm increase in central corneal thickness was associated with a 1.03 mm Hg (95% confidence interval, 0.79-1.26) increase in intraocular pressure after adjusting for age and sex. CONCLUSIONS: The changes in central corneal thickness values cause a significant variation in intraocular pressure in this population, suggesting that measurement of central corneal thickness will have implications in the diagnosis and management of glaucoma. |
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Authors:
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Suman S Thapa; Indira Paudyal; Shankar Khanal; Nabin Paudel; Steven L Mansberger; Ger H M B van Rens |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-4-13 |
Journal Detail:
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Title: Journal of glaucoma Volume: - ISSN: 1536-481X ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-4-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9300903 Medline TA: J Glaucoma Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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*Nepal Glaucoma Eye Clinic, Tilganga Institute of Ophthalmology †Central Department of Statistics, Tribhuvan University ‡Sudrishti Eye Clinic, Kathmanudu, Nepal §Devers Eye Institute, Portland, Oregon, USA ¶Vrije Universiteit Amsterdam, The Netherlands. |
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