Document Detail

Cemented endoprosthetic reconstruction of the proximal tibia: how long do they last?
MedLine Citation:
PMID:  20495967     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The few available studies documenting the long-term survival of cemented proximal tibial endoprostheses for musculoskeletal tumors do not differentiate between stem designs or patient diagnosis. There is wide variation in survival rates reported, possibly a result of this heterogeneity in patient population and implant design.
QUESTIONS/PURPOSES: We therefore asked: (1) How long do proximal tibial endoprostheses last? (2) What is the typical long-term functional result after proximal tibial replacement? And (3) what are the short- and long-term complications associated with endoprosthetic reconstruction of the proximal tibia, particularly with respect to the soft tissue reconstruction?
PATIENTS AND METHODS: We retrospectively reviewed 52 patients with 52 proximal tibial endoprosthetic reconstructions for a tumor-related diagnosis. Kaplan-Meier survivorship analysis was performed using revision of the stemmed components for any reason as an endpoint for implants, and death due to disease progression for patients. Function was assessed using the MSTS scoring system. The minimum followup was 1 month (mean, 96 months: range, 1-284 months; median, 69 months).
RESULTS: Using revision of the stemmed components for any reason as an end point, overall prosthesis survival at 5, 10, 15, and 20 years was 94%, 86%, 66%, and 37%, respectively. The 29 modular implants demonstrated a trend toward improved survival compared to the 23 custom-designed components, with a 15-year survivorship of 88% versus 63%. The mean postoperative Musculoskeletal Tumor Society score at most recent followup was 82% of normal function (mean raw score, 24.6; range, 4-29).
CONCLUSIONS: Cemented endoprosthetic reconstruction of the proximal tibia provides a reliable method of reconstruction following tumor resection.
Adam J Schwartz; J Michael Kabo; Fritz C Eilber; Frederick R Eilber; Jeffrey J Eckardt
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical orthopaedics and related research     Volume:  468     ISSN:  1528-1132     ISO Abbreviation:  Clin. Orthop. Relat. Res.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-09-30     Completed Date:  2010-10-21     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  0075674     Medline TA:  Clin Orthop Relat Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2875-84     Citation Subset:  AIM; IM    
Department of Orthopaedic Surgery, University of California Los Angeles Medical Center, Santa Monica, CA, USA.
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MeSH Terms
Bone Cements / therapeutic use*
Bone Neoplasms / mortality,  surgery*
Kaplan-Meier Estimate
Limb Salvage
Middle Aged
Orthopedic Procedures / instrumentation*
Prosthesis Design
Prosthesis Failure
Prosthesis Implantation / instrumentation*
Retrospective Studies
Tibia / surgery*
Time Factors
Treatment Outcome
Young Adult
Reg. No./Substance:
0/Bone Cements

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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