Document Detail


Cellular reprogramming in pursuit of immortality.
MedLine Citation:
PMID:  23217420     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The discovery that phenotypic diversity among differentiated cells results from epigenetic and not genetic differences, and can be reset to restore pluripotency, promises revolutionary advances in medicine. I discuss how this and related seminal discoveries have brought us to an exciting future.
Authors:
M Azim Surani
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cell stem cell     Volume:  11     ISSN:  1875-9777     ISO Abbreviation:  Cell Stem Cell     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-10     Completed Date:  2013-07-30     Revised Date:  2014-02-24    
Medline Journal Info:
Nlm Unique ID:  101311472     Medline TA:  Cell Stem Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  748-50     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Line, Transformed
Cloning, Organism
Epigenesis, Genetic
Humans
Induced Pluripotent Stem Cells / cytology
Mice
Nuclear Reprogramming / genetics*
Xenopus
Grant Support
ID/Acronym/Agency:
079249//Wellcome Trust

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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