| Cellular and molecular mechanics of gliding locomotion in eukaryotes. | |
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MedLine Citation:
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PMID: 16939778 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Gliding is a form of substrate-dependent cell locomotion exploited by a variety of disparate cell types. Cells may glide at rates well in excess of 1 microm/sec and do so without the gross distortion of cellular form typical of amoeboid crawling. In the absence of a discrete locomotory organelle, gliding depends upon an assemblage of molecules that links cytoplasmic motor proteins to the cell membrane and thence to the appropriate substrate. Gliding has been most thoroughly studied in the apicomplexan parasites, including Plasmodium and Toxoplasma, which employ a unique assortment of proteins dubbed the glideosome, at the heart of which is a class XIV myosin motor. Actin and myosin also drive the gliding locomotion of raphid diatoms (Bacillariophyceae) as well as the intriguing form of gliding displayed by the spindle-shaped cells of the primitive colonial protist Labyrinthula. Chlamydomonas and other flagellated protists are also able to abandon their more familiar swimming locomotion for gliding, during which time they recruit a motility apparatus independent of that driving flagellar beating. |
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Authors:
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Matthew B Heintzelman |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: International review of cytology Volume: 251 ISSN: 0074-7696 ISO Abbreviation: Int. Rev. Cytol. Publication Date: 2006 |
Date Detail:
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Created Date: 2006-08-30 Completed Date: 2006-10-18 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 2985180R Medline TA: Int Rev Cytol Country: United States |
Other Details:
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Languages: eng Pagination: 79-129 Citation Subset: IM |
Affiliation:
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Department of Biology, Program in Cell Biology and Biochemistry, Bucknell University, Lewisburg, PA 17837, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Actins
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metabolism Animals Apicomplexa / pathogenicity, physiology, ultrastructure Chlamydomonas / cytology, physiology Diatoms / physiology, ultrastructure Eukaryotic Cells / cytology, physiology* Humans Locomotion / physiology* Molecular Motor Proteins / metabolism Myosins / metabolism Protozoan Proteins / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Actins; 0/Molecular Motor Proteins; 0/Protozoan Proteins; EC 3.6.4.1/Myosins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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