Document Detail


Cellular migration in developing cerebral wall explants in vitro.
MedLine Citation:
PMID:  3359317     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Explants of the developing cerebral wall of the embryonic mouse survive in rotation-mediated culture for at least 3 days. [3H]Thymidine-labeled cells are initially located in the ventricular zone but after two days in vitro are located in a middle cell-rich layer. Cortical explants can thus be used as a model system in which the molecular mechanisms of neuronal migration in the developing cerebral wall can be examined.
Authors:
L M Hemmendinger; V S Caviness
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Brain research     Volume:  466     ISSN:  0006-8993     ISO Abbreviation:  Brain Res.     Publication Date:  1988 Feb 
Date Detail:
Created Date:  1988-05-27     Completed Date:  1988-05-27     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0045503     Medline TA:  Brain Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  291-5     Citation Subset:  IM    
Affiliation:
Southard Laboratory of Neuropathology, E.K. Shriver Center, Waltham, MA 02254.
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Division
Cell Movement
Cells, Cultured
Cerebral Cortex / cytology,  embryology*,  physiology
Epithelial Cells
Epithelium / embryology,  physiology
Mice
Mice, Inbred C3H
Mice, Inbred C57BL
Stem Cells / cytology*,  physiology
Thymidine
Grant Support
ID/Acronym/Agency:
HD-04147/HD/NICHD NIH HHS; NS-120059/NS/NINDS NIH HHS
Chemical
Reg. No./Substance:
50-89-5/Thymidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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