| Cellular mechanisms underlying EEG waveforms during coma. | |
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MedLine Citation:
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PMID: 21967355 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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This paper describes the various electroencephalographic (EEG) patterns expressed by the comatose brain, starting with the sleep-like oscillations associated with light coma. Deeper coma generally displays a burst-suppression pattern characterized by alternating episodes of isoelectric (flat) EEG and bursting slow waves. The latter are the result of cortical hyperexcitability, as demonstrated by intracellular recordings in anesthetized animals. Further deepening of the coma yields to continuous isoelectric EEG and eventually results in a newly discovered type of spiky waves that have been termed ν-complexes. They originate in the hippocampus as a result of intrinsically generated oscillations (ripples) in the delta range. |
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Authors:
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Florin Amzica; Daniel Kroeger |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Epilepsia Volume: 52 Suppl 8 ISSN: 1528-1167 ISO Abbreviation: Epilepsia Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-04 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2983306R Medline TA: Epilepsia Country: United States |
Other Details:
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Languages: eng Pagination: 25-7 Citation Subset: IM |
Copyright Information:
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Wiley Periodicals, Inc. © 2011 International League Against Epilepsy. |
Affiliation:
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Université de Montreal, Montreal, Quebec, Canada. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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