Document Detail

Cellular mechanisms in hypertension and therapeutic implications in blacks.
MedLine Citation:
PMID:  2271397     Owner:  NLM     Status:  MEDLINE    
The high incidence and prevalence of hypertension in the black community in western societies led to early speculation that the black population consumed more sodium (sodium chloride) than the general population. However, numerous studies have failed to support this conclusion. It seems rather that it is the handling of sodium by the kidney (greater salt sensitivity) by many hypertensive blacks and the interaction of sodium with potassium, probably magnesium, calcium, and various transport systems at the cellular level that offer a better explanation of these observed phenomena.
E Saunders
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy     Volume:  4 Suppl 2     ISSN:  0920-3206     ISO Abbreviation:  Cardiovasc Drugs Ther     Publication Date:  1990 Mar 
Date Detail:
Created Date:  1991-02-22     Completed Date:  1991-02-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8712220     Medline TA:  Cardiovasc Drugs Ther     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  317-9     Citation Subset:  IM    
Department of Medicine, University of Maryland School of Medicine and Hospital, Baltimore 21201.
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MeSH Terms
African Continental Ancestry Group*
Biological Transport
Electrolytes / metabolism
Hypertension / ethnology,  metabolism*
Kidney / metabolism
Sodium, Dietary / metabolism
United States / epidemiology
Reg. No./Substance:
0/Electrolytes; 0/Sodium, Dietary

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