Document Detail


Cellular immunity to Hodgkin's splenic tissue measured by leucocyte migration inhibition.
MedLine Citation:
PMID:  1260271     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Patients with lymphoreticular malignancy were shown by a leucocyte migration inhibition technique to have cellular immunity to Hodgkin's splenic tissue. Migration was significantly inhibited in 31 out of 55 patients with Hodgkin's lymphoma and 19 out of 39 patients with other types of lymphoma. Inhibition was also shown in only three out of 29 patients with other malignancy, one out of 23 normal volunteers, and one out of 25 patients with non-malignant disease. The splenic factor that inhibits leucocyte migration, which has yet to be isolated and identified, may be a helpful diagnostic tool in patients with suspected lymphoma.
Authors:
B W Hancock; L Bruce; J Richmond
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British medical journal     Volume:  1     ISSN:  0007-1447     ISO Abbreviation:  Br Med J     Publication Date:  1976 Mar 
Date Detail:
Created Date:  1976-07-06     Completed Date:  1976-07-06     Revised Date:  2010-09-07    
Medline Journal Info:
Nlm Unique ID:  0372673     Medline TA:  Br Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  556-7     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Cell Migration Inhibition
Hodgkin Disease / immunology*
Humans
Immunity, Cellular
Leukocytes
Lymphoma / immunology
Spleen / immunology*
Comments/Corrections

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