Document Detail


Cellular immune responses and susceptibility to HIV-1 superinfection: a case-control study.
MedLine Citation:
PMID:  22210637     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A case control study was performed to determine the effects of HIV-1-specific cellular immune responses on the odds of acquiring a second HIV-1 infection (superinfection). Changes in the frequency of cytokine-producing or cytolytic CD8+ or CD4+ T cells were not associated with significant alterations in the odds of superinfection, suggesting that HIV-1 specific cellular immune responses at the level induced by chronic infection do not appear to significantly contribute to protection from HIV-1 superinfection.
Authors:
Catherine A Blish; Ozge C Dogan; Walter Jaoko; R Scott McClelland; Kishorchandra Mandaliya; Katherine Odem-Davis; Barbra A Richardson; Julie Overbaugh
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-29
Journal Detail:
Title:  AIDS (London, England)     Volume:  -     ISSN:  1473-5571     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2012-1-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8710219     Medline TA:  AIDS     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
aDivision of Human Biology bDepartments of Medicine cDepartment of Medical Microbiology, University of Nairobi, Nairobi, Kenya dGlobal Health eCoast General Hospital, Mombasa, Kenya. fBiostatistics University of Washington, Seattle, WA gVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
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