Document Detail


Cellular envelope phospholipids from Legionella lytica.
MedLine Citation:
PMID:  18462396     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The composition of phospholipids from the cellular envelope of Legionella lytica grown on artificial medium was determined by two-dimensional thin-layer chromatography. Phosphatidylcholine, phosphatidylethanolamine, and phosphatidyl-N-monomethylethanolamine were the predominant phospholipids, while diphosphatidylglycerol, phosphatidylglycerol, and phosphatidyl-N,N-dimethylethanolamine were present at low concentrations. A trace amount of lipids carrying glycosyl residues was also observed. The fatty acids and their distribution in individual phospholipids were characterized using liquid chromatography/mass spectrometry (LC/MS), matrix-assisted laser desorption ionization-time of flight, and gas chromatography/MS methods. The characteristic feature of L. lytica phospholipids was the presence of an unbranched chain (which differentiates this bacterium from Legionella pneumophila) and branched iso and anteiso fatty acids as well as cis-9,10-methylenehexadecanoic acid. According to spectroscopic LC/MS data, the localization of saturated and unsaturated fatty acid residues on phosphorylglycerol was determined. Some aspects of the significance of phosphatidylcholine, one of the main phospholipids in L. lytica, are addressed and taxonomic implications of the data are discussed.
Authors:
Marta Palusinska-Szysz; Rafal Kalitynski; Ryszard Russa; Andrzej L Dawidowicz; Wincenty J Drozanski
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-05-06
Journal Detail:
Title:  FEMS microbiology letters     Volume:  283     ISSN:  0378-1097     ISO Abbreviation:  FEMS Microbiol. Lett.     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-05-15     Completed Date:  2008-07-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7705721     Medline TA:  FEMS Microbiol Lett     Country:  England    
Other Details:
Languages:  eng     Pagination:  239-46     Citation Subset:  IM    
Affiliation:
Department of General Microbiology, Maria Curie-Sklodowska University, Akademicka St. 19, Lublin, Poland. martasz@biotop.umcs.lublin.pl
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MeSH Terms
Descriptor/Qualifier:
Cell Membrane / chemistry*
Chromatography, Liquid
Chromatography, Thin Layer / methods
Fatty Acids / analysis,  isolation & purification
Fatty Acids, Unsaturated / analysis,  isolation & purification
Gas Chromatography-Mass Spectrometry
Legionella / chemistry*
Mass Spectrometry
Phospholipids / analysis*,  isolation & purification
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Chemical
Reg. No./Substance:
0/Fatty Acids; 0/Fatty Acids, Unsaturated; 0/Phospholipids

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