Document Detail


Cellular distribution of okadaic acid in the digestive gland of Mytilus galloprovincialis (Lamarck, 1819).
MedLine Citation:
PMID:  18926843     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The distribution of okadaic acid between the digestive and the secretory cells of the digestive gland of Mytilus galloprovincialis was studied for the main purpose of determining if they might be responsible for the two-compartment depuration kinetics found in previous studies. The two cell types did not accumulate okadaic acid to the same degree. However, the concentrations found in each cellular type were not consistent with those expected from the output of the two-compartment depuration model, suggesting that a mechanism other that the differential accumulation in cellular types is involved. Binding to some yet undetermined cellular components is suggested.
Authors:
Araceli E Rossignoli; Juan Blanco
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-09-27
Journal Detail:
Title:  Toxicon : official journal of the International Society on Toxinology     Volume:  52     ISSN:  0041-0101     ISO Abbreviation:  Toxicon     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-12-05     Completed Date:  2009-03-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1307333     Medline TA:  Toxicon     Country:  England    
Other Details:
Languages:  eng     Pagination:  957-9     Citation Subset:  IM    
Affiliation:
Centro de Investigacións Mariñas (CIMA), Pedras de Corón, s/n. Apdo. 13, 36620 Vilanova de Arousa (Pontevedra), Spain.
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MeSH Terms
Descriptor/Qualifier:
Animals
Chromatography, High Pressure Liquid
Digestive System / cytology,  metabolism
Marine Toxins / metabolism
Models, Biological
Mytilus / metabolism*
Okadaic Acid / metabolism*
Spectrometry, Mass, Electrospray Ionization
Tissue Distribution
Chemical
Reg. No./Substance:
0/Marine Toxins; 78111-17-8/Okadaic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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