Document Detail

Cellular death but not genetic damage in oral mucosa cells after exposure to digital lateral radiography.
MedLine Citation:
PMID:  20336472     Owner:  NLM     Status:  In-Data-Review    
The aim of the present study was to evaluate DNA damage (micronucleus) and cellular death (pyknosis, karyolysis, and karyorrhexis) in exfoliated buccal mucosa cells from individuals following digital lateral radiography. A total of 30 healthy patients (15 men and 15 women) indicated to the orthodontic therapy were submitted to digital lateral X-ray. Exfoliated oral mucosa cells were collected immediately before the X-ray exposure and after 10 days. The results pointed out no significant statistically differences (p > 0.05) of micronucleated oral mucosa cells. On the other hand, X-ray was able to increase other nuclear alterations closely related to cytotoxicity such as karyorrhexis, pyknosis, and karyolysis. In summary, these data indicate that exposure to digital lateral radiography may not be a factor that induced chromosomal damage, but it is able to promote cytotoxicity.
Daniel A Ribeiro; Eduardo K Sannomiya; Renan Pozzi; Sandra R Miranda; Fernanda Angelieri
Publication Detail:
Type:  Journal Article     Date:  2010-03-25
Journal Detail:
Title:  Clinical oral investigations     Volume:  15     ISSN:  1436-3771     ISO Abbreviation:  Clin Oral Investig     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9707115     Medline TA:  Clin Oral Investig     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  357-60     Citation Subset:  D    
Departamento de Patologia, Universidade Federal de Sao Paulo, São Paulo, Brazil,
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