| Cellular chemical indices of right ventricular protection in children. | |
| | |
MedLine Citation:
|
PMID: 6215386 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Myocardial preservation during open heart surgery in children was studied using biopsies of the right ventricle taken at the beginning and end of a bypass with a Tru-Cut biopsy needle. Three assessments were used: (1) semi-quantitative cytochemical grading of Baker's acid haematein reaction, and the distribution of succinate dehydrogenase and myosin ATPase; (2) microdensitometry of the succinate dehydrogenase activity; and (3) quantitative birefringence measurements to assess the response of the myocardial fibres to ATP and calcium. For each assessment, the values at the beginning and end of the bypass were compared. In a series of 42 children, two died in low cardiac output and three others required substantial inotropic support. No patient showed deterioration in the overall cytochemical assessment. Two patients showed deterioration in birefringence, one died and one had low cardiac output. The remaining three patients who had post-operative problems had low birefringence values at the beginning of bypass. Thirty-two patients were used for the microdensitometric assays, one died and three required substantial inotropic support. Succinate dehydrogenase activity decreased significantly during bypass in only two patients. One of these died and the other required substantial inotropic support. |
| | |
Authors:
|
J Cooper; C Bull; S Canković-Darracott; J Stark |
Related Documents
:
|
10469966 - Effect of posterior pericardiotomy on postoperative supraventricular arrhythmias and la... 18754936 - Constrictive pericarditis impressing and narrowing the ascending aorta. 230966 - Aerobic lactate synthesis by cardiac muscle. 16341966 - The diagnosis of cardiac dysfunction in critically iii trauma patients with blunt chest... 12208226 - Comparative outcomes of percutaneous coronary interventions in diabetics vs non-diabeti... 10558446 - Enoxaparin and dalteparin in unstable angina: new indication. enoxaparin: a reference t... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: The Histochemical journal Volume: 14 ISSN: 0018-2214 ISO Abbreviation: Histochem. J. Publication Date: 1982 Sep |
Date Detail:
|
Created Date: 1982-12-16 Completed Date: 1982-12-16 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0163161 Medline TA: Histochem J Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 739-46 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adenosine Triphosphatases
/
analysis Biopsy Birefringence Child Child, Preschool Heart Defects, Congenital / surgery* Heart Ventricles / enzymology Histocytochemistry Humans Infant Myocardium / enzymology*, pathology Succinate Dehydrogenase / analysis |
| Chemical | |
Reg. No./Substance:
|
EC 1.3.99.1/Succinate Dehydrogenase; EC 3.6.1.-/Adenosine Triphosphatases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Use of microstereology and quantitative cytochemistry to determine the effects of crude oil-derived ...
Next Document: Analysis of volume displacement and length changes of the diaphragm during breathing.