| Cellular Localization of Inhibin alpha-subunit, PKB/Akt and FoxO3a proteins in the ovaries of minipigs. | |
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MedLine Citation:
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PMID: 17132910 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Experiments were conducted to examine the cellular localization of inhibin alpha-subunit, protein kinase B (PKB/Akt), and FoxO3a proteins in the ovaries of minipigs, Chinese Xiang pigs, by immunohistochemistry. The results indicated that inhibin alpha-subunits were localized in the granulosa cells of follicles at all stages but were not localized in corpora lutea. PKB was localized in the granulosa cells of primordial follicles and in the basal layers of the granulosa cells of preantral and antral follicles, but were not localized in atretic follicles and corpora lutea. FoxO3a was localized in the granulosa cells of follicles at all stages and was extensively localized in the cytoplasma of the luteinized granulosa cells of corpora lutea. Together, the stage- and cell-specific expression patterns of inhibin alpha-subunit, FoxO3a, and PKB suggest that these proteins might play potential roles in follicular development, atresia, and luteinization in the minipig. |
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Authors:
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Chunhua Meng; Fangxiong Shi; Zhenqi Zhou; Ruihua Huang; Gentao Liu; Gen Watanabe; Kazuyoshi Taya |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2006-11-29 |
Journal Detail:
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Title: The Journal of reproduction and development Volume: 53 ISSN: 0916-8818 ISO Abbreviation: J. Reprod. Dev. Publication Date: 2007 Apr |
Date Detail:
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Created Date: 2007-05-17 Completed Date: 2007-06-18 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 9438792 Medline TA: J Reprod Dev Country: Japan |
Other Details:
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Languages: eng Pagination: 229-36 Citation Subset: IM |
Affiliation:
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Laboratory of Animal Reproduction, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, PR China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cytoplasm / metabolism Female Forkhead Transcription Factors / metabolism* Granulosa Cells / metabolism Immunohistochemistry / methods Inhibins / metabolism* Ovary / cytology*, physiology Proto-Oncogene Proteins c-akt / metabolism* Swine Swine, Miniature |
| Chemical | |
Reg. No./Substance:
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0/Forkhead Transcription Factors; 0/inhibin-alpha subunit; 57285-09-3/Inhibins; EC 2.7.11.1/Proto-Oncogene Proteins c-akt |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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